1-isopropyl-3,5-dimethyl-1H-pyrazole-4-carboxylic acid
1-Isopropyl-3,5-dimethyl-1H-pyrazole-4-carboxylic acid
CAS: 1007542-01-9
Molecular Formula: C9H14N2O2
1-isopropyl-3,5-dimethyl-1H-pyrazole-4-carboxylic acid - Names and Identifiers
1-isopropyl-3,5-dimethyl-1H-pyrazole-4-carboxylic acid - Physico-chemical Properties
| Molecular Formula | C9H14N2O2 |
| Molar Mass | 182.22 |
| Density | 1.17±0.1 g/cm3(Predicted) |
| Boling Point | 306.0±37.0 °C(Predicted) |
| pKa | 3.77±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD06260701 |
1-isopropyl-3,5-dimethyl-1H-pyrazole-4-carboxylic acid - Risk and Safety
| Hazard Class | IRRITANT |
1-isopropyl-3,5-dimethyl-1H-pyrazole-4-carboxylic acid - Introduction
Isopropyl-3, 1-acid is an organic compound with the chemical formula C9H12N2O2. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: 1-Isopropyl-3, acid is a colorless crystalline solid.
-Solubility: It is not easily soluble in water, but easily soluble in organic solvents such as ether, chloroform and butanol.
-Melting point: Its melting point is about 128-130°C.
-Stability: 1-Isopropyl-3, acid is a relatively stable compound, but contact with strong oxidants and strong acids should be avoided.
Use:
- 1-Isopropyl-3, acid is commonly used as an intermediate in organic synthesis to prepare other compounds or drugs.
-It is also studied in the field of medicine for the synthesis of antitumor and antiviral drugs.
Preparation Method:
1-Isopropyl-3, the preparation method of acid includes the following steps:
1. 2-Acetylpyridine is obtained by reacting 2-pyridone with acetic anhydride.
2. In the presence of ammonia, 2-acetylpyridine and methyl isopropyl ketone react to generate 3,5-dimethyl -1-(propan-2-yl)-1H-pyrazole.
3. Finally, by reacting 3,5-dimethyl-1-(propan-2-yl)-1H-pyrazole with trifluoroacetic acid, 1-Isopropyl-3, oxadiazole was obtained.
Safety Information:
- 1-Isopropyl-3, Relevant safety information and protective measures of the acid should be determined according to the specific use and the safety procedures of the chemist or laboratory.
-When handling the compound, wear appropriate protective equipment, such as gloves, goggles and protective clothing.
-Avoid inhaling its powder or vapor, and keep away from fire and high temperature environment.
-During use, the laboratory should be kept well ventilated.
-If taken by mistake or inhaled, seek medical attention immediately.
Nature:
-Appearance: 1-Isopropyl-3, acid is a colorless crystalline solid.
-Solubility: It is not easily soluble in water, but easily soluble in organic solvents such as ether, chloroform and butanol.
-Melting point: Its melting point is about 128-130°C.
-Stability: 1-Isopropyl-3, acid is a relatively stable compound, but contact with strong oxidants and strong acids should be avoided.
Use:
- 1-Isopropyl-3, acid is commonly used as an intermediate in organic synthesis to prepare other compounds or drugs.
-It is also studied in the field of medicine for the synthesis of antitumor and antiviral drugs.
Preparation Method:
1-Isopropyl-3, the preparation method of acid includes the following steps:
1. 2-Acetylpyridine is obtained by reacting 2-pyridone with acetic anhydride.
2. In the presence of ammonia, 2-acetylpyridine and methyl isopropyl ketone react to generate 3,5-dimethyl -1-(propan-2-yl)-1H-pyrazole.
3. Finally, by reacting 3,5-dimethyl-1-(propan-2-yl)-1H-pyrazole with trifluoroacetic acid, 1-Isopropyl-3, oxadiazole was obtained.
Safety Information:
- 1-Isopropyl-3, Relevant safety information and protective measures of the acid should be determined according to the specific use and the safety procedures of the chemist or laboratory.
-When handling the compound, wear appropriate protective equipment, such as gloves, goggles and protective clothing.
-Avoid inhaling its powder or vapor, and keep away from fire and high temperature environment.
-During use, the laboratory should be kept well ventilated.
-If taken by mistake or inhaled, seek medical attention immediately.
Last Update：2024-04-09 21:00:56
